[Research Achievements] Paper published in AAPS PharmSciTech.
The paper by Yoshihiro Omachi from our company's Formulation Technology Research Headquarters has been published in the academic journal "AAPS PharmSciTech" issued by the American Pharmacists Association.
Gastric retention drug delivery systems (GRDDS) are a formulation technology that retains orally administered formulations in the stomach to gradually release the drug, thereby delaying the transition of the drug to the small intestine and sustaining drug absorption. However, drugs that are difficult to dissolve or unstable in acidic environments have been considered unsuitable for GRDDS. In this study, we designed a GRDDS combined with a self-microemulsifying drug delivery system (SMEDDS) for drugs that have issues with solubility and stability in the stomach.
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